$188K – $288KExecutiveFull Time
Introduction to role:
Are you ready to harness statistical science to accelerate breakthroughs for patients with cancer? In this leadership role, you will set the statistical vision that turns complex data into clear decisions across discovery, development, and commercialization. Your work will directly influence which molecules move forward, how studies are designed, and how regulators and payers view the value of our medicines.
You will guide a talented team, bring novel methodology to life, and collaborate across clinical, regulatory, and market access to develop product profiles. Can you see yourself quantifying benefit–risk with confidence, crafting submission-ready evidence, and mentoring statisticians to raise the bar every day? If so, this is your opportunity to leave a measurable imprint on a pipeline poised for its most exciting chapter.
Accountabilities:
SHE Stewardship: Work according to agreed functional and regional SHE strategy by ensuring accurate management of SHE risks, incidents, reporting, follow-up and improvements.
Statistical Design and Strategy: Lead the statistical design and strategy to product development plans, preclinical studies, regulatory strategy, health technology assessment and/or commercial activities as appropriate for the stage of the product.
Study Excellence and Submissions: Lead the statistical content and ensure quality for study designs, documents, delivery and interpretation and submission.
Benefit–Risk and Uncertainty: Quantify the benefit, risk, value and uncertainty of the emerging product profile and communicate these effectively within the team.
Global Leadership and Delivery: Provide global leadership to others and direct project work delivered by internal and external staff; partner with CROs to ensure delivery to quality and time.
External Representation: Represent AZ externally which may include health authorities, advisory boards, conferences, workshops and/or payer interactions.
Methodology Innovation: Maintain knowledge of statistical methodology in relevant areas and promote, investigate and implement novel statistical approaches.
Governance and Decision Making: Represent statistical strategy and decision making at internal decision-making governance including review boards, therapy area leadership teams and ESPC/LSPC.
Talent Development: Mentor/coach and support the technical education and training of Statistics staff.
Essential Skills/Experience:
MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognized equivalent to stats MSc
In-depth knowledge of technical/regulatory requirements with experience in pharm/healthcare
Up to date and implements novel stats approaches
Experience with and broad awareness of regulatory interactions and/or submissions
Excellent communication skills/ build strong relationships
Nationally recognized externally. Encouraged to attend or speak at seminars and external meetings. Well-rounded statistician with publications on a range of topic areas. Publications resulting from external collaborations
Guide Leadership role able to lead/direct work across a team
Track record leading statistical strategy across multiple indications, including sophisticated oncology programs
Deep expertise in adaptive, Bayesian, and model-based build methods for late-stage and lifecycle evidence generation
Experience crafting health technology assessment strategy and payer evidence, including endpoints, estimands, and comparative efficiency
Strong proficiency with modern statistical computing environments and programming languages, and oversight of production-quality deliverables from CROs
Success building high-performing, diverse teams across geographies and integrating external collaborations with academia and consortia
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
The annual base pay for this position ranges from $188279 to $288,419. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Why AstraZeneca:
Here, ambitious science meets decisive action to change outcomes for people with cancer. You will join a collaborative community that unites industry and academia, fuses cutting-edge methodology with data and technology, and empowers leaders at every level to ask bold questions and take smart risks. With a pipeline rich in high-quality molecules across multiple stages and a clear path to bringing new medicines to patients, your statistical leadership will translate directly into clinical progress and real-world impact. We value kindness alongside ambition, and we back courageous ideas with the support and resources to make them real.
Call to Action:
Step into a Director, Statistics role where your judgment, innovation, and leadership will accelerate transformative medicines—bring your expertise and help write the next chapter now.
Date Posted
18-May-2026Closing Date
30-Jul-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
