Associate Director, Pharmacovigilance (PV) Commercial Liaison, Global Clinical Safety and Pharmacovigilance

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Reporting to the Senior Director, Global Clinical Safety and Pharmacovigilance, the PV Commercial Liaison provides operational oversight to ensure that all post-marketing safety reporting obligations are met in commercial programs, including marketing campaigns, patient support initiatives, and medical affairs activities. This role is key in ensuring alignment and compliance between the Pharmacovigilance and Commercial functions across the organization.

This role will additionally serve as the Local Person for Pharmacovigilance (LPPV) in Switzerland, ensuring compliance with Swiss PV regulations for products marketed in Switzerland, with an indirect reporting line to the EU Qualified Person for Pharmacovigilance (QPPV).

Key PV Commercial Liaison Responsibilities

• Act as the PV point of contact for assigned Commercial and Medical Affairs teams
• Represent PV in project teams, vendor meetings, and internal initiatives that involve external-facing activities
• Coordinate and deliver targeted training for commercial, field-based, and medical team on safety reporting obligations
• Ensure all required service providers and external vendors receive training on safety reporting obligations
• Support the development of SOPs and training materials specific to commercial PV interfaces.
• Maintain oversight of PV responsibilities within commercial contracts and vendor relationships
• Monitor metrics and KPIs related to AE reporting compliance from commercial sources
• Meet regularly or ad hoc with Commercial vendor leads to discuss AE report trends to support continuous improvement
• Primary Contributor for assigned Modules and Annexes of the Pharmacovigilance System Master File (PSMF)
• Perform additional tasks, as directed by management

Key LPPV Responsibilities

• Serve as the designated local PV contact for Switzerland
• Be available to Swissmedic for inspections, product recalls or urgent safety queries
• Ensure alignment with global PV system
• Maintain local PSMF, as required
• Work closely with the QPPV Office Lead and participate in regular LPPV meetings
• Collaborate with the global PV team and EU QPPV on PV matters, as required

 Qualifications and Skills Required:

• Bachelor’s degree in relevant scientific discipline. Clinical experience (e.g. Clinical/Medical experience and / or Pharmacovigilance certification preferred
• Drug Safety professional with a minimum of 8 years of experience within global drug safety and PV inclusive of case quality control and regulatory submissions of ICSRs worldwide
• Experience in managing teams and external vendors, including indirect management
• Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities.
• Excellent communication skills and ability to influence multiple functions
• Strong regulatory knowledge of Swiss PV framework
• Knowledge of global safety reporting requirements
• Experience with coordinating and participating in audits and local PV regulatory inspections

We are committed to fostering an inclusive and diverse workplace and do not discriminate on the basis of any legally protected characteristics. Madrigal processes your personal data in connection with its recruitment and talent sourcing activities in accordance with applicable data protection laws. Further information about how your personal data is processed, together with details of your rights and how to exercise them, is available in our Job Applicant Privacy Notice, which is made available to you if you apply through Workday.

Please note that this job description is not exhaustive and may evolve over time. Only shortlisted candidates will be contacted. Applicants must be authorized to work in the country of employment at the time of application. Employment terms, where applicable, will be governed by relevant collective bargaining agreements.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.